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While snca gene (wild-type) is involved in sporadic Morbus Parkinson / Parkinson's Disease (PD) cases, Alfa-Synuclein (SNCA) (MUT) is particularly significant in familial Morbus Parkinson / Parkinson's Disease (PD)
Morbus Parkinson / Parkinson's Disease (PD) associated with alfa-synuclein (SNCA) mutation is early-onset, moderately responses to levodopa treatment, progresses rapidly, where psychiatric symptom manifestations and cognitive decline are evident
Tysnes & Storstein 2017 J Neural Transm (vien…