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Cobamides, particularly vitamin B12, are essential for the growth and metabolism of many gut bacteria. Some gut microbes can synthesize cobamides, while others rely on external sources or cross-feeding from other bacteria
The presence and availability of cobamides in the gut can influence the composition and function of the gut microbiota. This, in turn, can affect various aspects of human health:
(1) Nutrient Metabolism: Cobamides are involved in important metabolic pathways, including the breakdown of [Complex carbohydrates …