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The skin, lungs, and intestines are always in contact with the environment, which can lead to inflammation and damage. Group 2 ILCs (ILC2), which depend on Interleukin-33 (IL-33), are found in large numbers at these barrier surfaces. They are known to play a role in inflammation, but how they help protect tissues, especially in the intestines, is not well understood.
When Group 2 ILCs (ILC2) in t…