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The gut microbiota of patients with shingles or Postherpetic neuralgia (PHN) showed significant changes. Microbial markers were able to predict the development of PHN in those with shingles. Transplanting the fecal microbiota from patients with PHN into mice led to an increase in pain sensitivity.
In a study involving mice, the administration of Roseburia intestinalis, a bacterium that is often found to be lacking in patients suffering from shingles and postherpetic neuralgia (PHN), was show…