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Biliary tract cancer / Cholangiocarcinoma has the most actionable genomic targets of the hepatobiliary malignancies, including mutations in Isocitrate Dehydrogenase (IDH) and Fibroblast Growth Factor Receptor (FGFR), particularly CD332 (Fibroblast growth factor receptor 2 (FGFR2)
Biliary tract cancers exhibit one of the highest frequencies of targetable molecular alterations across cancer types.
Alterations in DNA damage repair (DDR) genes are observed in up…