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Adoptive T Cell Therapy / CAR-T is an important treatment modality in acute lymphoblastic leukemia (ALL), with the strongest clinical impact so far in relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) and a rapidly evolving but still more experimental role in T-ALL / T-Cell Acute Lymphoblastic Leukemia. In B-ALL, CD19-directed CAR-T has moved into standard practice for selected relapsed/refractory patients, while in T-ALL the main challenge is that malignant an…