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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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MAPK / ERK Pathway & Melanoma (cutaneous)

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The extracellular signal-regulated MAPK / ERK Pathway plays a crucial role in the development and progression of Melanoma (cutaneous). The MAPK / ERK Pathway is often constitutively activated in melanoma due to mutations in upstream components such as BRAF and NRAS.
Savoia et al. 2019 Int J Mol Sci. 20(6): 1483

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References (Sources)

New perspectives on targeting RAF, MEK and ERK in melanoma
Dumaz & Lebbé 2021 Current Opinion in Oncology 33: 120-126
Targeting the ERK Signaling Pathway in Melanoma
Savoia et al. 2019 Int J Mol Sci. 20(6): 1483
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MAPK / ERK Pathway & Melanoma (cutaneous)

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