Medical Research Finder

Start
Features
Free trial / FAQ

Researchers
Physicians
Pharmacists
Ecotrophologists
Product Managers
in Health Industries

Loading…

© 2026 meRfi®

Medical Research Finder

Legal Notice
Privacy
Terms of Use

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

meRfi® AI Chat

LL-37 / Cathelicidin antimicrobial peptide

Welcome to meRfi Microbiome!

Please register to continue your trial period!

meRfi Microbiome provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.

Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.

Start your free trial and transform your understanding of the gut microbiota today!

Register for a free trial

Navigation

Contents

Cathelicidin (LL37) has antimicrobial and immunomodulating properties. It plays a crucial role in the innate immune system. Its precursor is hCAP18
Noguès et al. 2022 Sci Rep 12: 15641

Cathelicidin production by the colonic epithelium is increased by activation of FXR
Campbell et al. 2012 Eur J Nutr 51(8): 899–907

see also:
Inflammation / Inflammatory Diseases & Neutrophils / Neutrophilic Granulocytes
Lactococcus lactis (genetically modified)
[Lactococcus lactis LL-pSEC:hCAP18](brain://1ewc5SXmME6b08v3IBYNOQ/Lacto…

References (Sources)

Cathelicidin-related antimicrobial peptide (CRAMP) is toxic during neonatal murine influenza virus infection
Rao et al. 2025 The Journal of Immunology 214(5): 1022-1031
Cell Differentiation Is a Key Determinant of Cathelicidin LL-37/Human Cationic Antimicrobial Protein 18 Expression by Human Colon Epithelium
Hase et al. 2002 Infect Immun 70 (2): 953–63
Degradation of human antimicrobial peptide LL-37 by Staphylococcus aureus-derived proteinases
Sieprawska-Lupa et al. 2004 Antimicrob Agents Chemother 48: 46734679
Lactococcus lactis engineered to deliver hCAP18 cDNA alleviates DNBS-induced colitis in C57BL/6 mice by promoting IL17A and IL10 cytokine expression
Noguès et al. 2022 Sci Rep 12: 15641
Regulation of antimicrobial peptide gene expression by nutrients and by-products of microbial metabolism
Campbell et al. 2012 Eur J Nutr 51(8): 899–907
Targeting Impaired Antimicrobial Immunity in the Brain for the Treatment of Alzheimer’s Disease
Fulop et al. 2021 Neuropsychiatric Disease and Treatment 17: 1311-1339
Review

AI Chat

7/1/2026

Chat with our artificial intelligence:

Links

Cathelicidin antimicrobial peptide - Wikipedia