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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Tryptophan 2,3 Dioxygenase (TDO) inhibitors

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Tryptophan 2,3 Dioxygenase Inhibitors has the potential to alleviate both motor and non-motor dysfunctions in Morbus Parkinson / Parkinson's Disease (PD). However, there are concerns about the harmful effects of long-term Tryptophan 2,3 Dioxygenase (TDO) inhibition.

References:
Boros & Vécsei 2021 Expert Opinion on Therapeutic Targets 25(10): 877-888

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Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors
Schramme et al. 2020 Cancer Immunology Research 8: 32
Tryptophan 2,3-dioxygenase, a novel therapeutic target for Parkinson’s disease
Boros & Vécsei 2021 Expert Opinion on Therapeutic Targets 25(10): 877-888
Review

7/1/2026