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In the context of Ponatinib & Acute Lymphoblastic Leukemia (ALL) (Ph+ ALL), ponatinib a third-generation TKI is FDA‑approved for Acute Lymphoblastic Leukemia (ALL) (Ph+ ALL), both in the front‑line combination setting and in later‑line monotherapy‑like indications (1, 2)
(1) fda-grants-accelerated-approval-ponatinib-chemotherapy-newly-diagnosed-philadelphia-chromosome
(2)
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