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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Inulin-type fructans (ITF) / Inulin & Metabolic diseases / Metabolic disorders

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Inulin-type fructans (ITF) / Inulin can alleviate metabolic disorders by remodeling the gut microbiota and increasing the production of SCFAs, possibly mediated by the ANGPTL4-related pathway in mice
Guo et al. 2022 J Food Biochem. 46: e14063

It has a cholesterol-lowering effect and is effective in preventing metabolic disturbances induced by High-fat diet (HFD) in mice
Albouery et al. 2021 Nutrients …

References (Sources)

Designing future prebiotic ﬁber to target metabolic syndrome
Jakobsdottir et al. 2014 Nutrition 30: 497-502
Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety.
Brooks et al. 2017 Mol. Metab. 6: 48-60
Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health
Zou et al. 2018 Cell Host Microbe 23: 41-53.e44
Inulin Exerts Beneficial Effects on Non-Alcoholic Fatty Liver Disease via Modulating gut Microbiome and Suppressing the Lipopolysaccharide-Toll-Like Receptor 4-Mψ-Nuclear Factor-κB-Nod-Like Receptor Protein 3 Pathway via gut-Liver Axis in Mice
Bao et al. 2020a Front. Pharmacol. 11: 558525
Inulin-type fructans modulate intestinal Biﬁdobacterium species populations and decrease fecal short-chain fatty acids in obese women
Salazar et al. 2015 Clin. Nutr. 34: 501-507
Isoquercetin and inulin synergistically modulate the gut microbiome to prevent development of the metabolic syndrome in mice fed a high fat diet
Tan et al. 2018a Sci. Rep. 8: 10100
Mechanisms used by inulin-type fructans to improve the lipid proﬁle
Reis et al. 2014 Nutr. Hosp. 31: 528-534

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