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Colonization of the maternal microbiota prevents neurodevelopmental abnormalities induced by microbiome depletion
The maternal microbiota modulates maternal serum and fetal brain metabolites during pregnancy
Depletion of the maternal microbiota impairs fetal thalamocortical axonogenesis
During pregnancy, a characteristic of the maternal microbiota is the translocation of bacteria from the mother's oral microbiota and gut microbiota. In addition, bacteria can ascend from the Cervicovaginal microbiome / Vaginal microbiota. These processes could explain the presence of non-pathogenic bacteria at intrauterine sites.
Furthermore, the detection of maternal bacteria in the newborn's meconium suggests that bacteria are transmitted prenatally from mother to child. This suggests that the maternal microbiota plays a crucial role in shaping the newborn's initial microbial environment.
The maternal Gut microbiota can influence the prenatal development of the blood brain barrier
see also:
Intestinal immune system