Intestinal immune system

Where are memory T cells found before birth?

Memory T cells are found in various fetal tissues, including the intestines of humans and nonhuman primates (1, 2, 3, 4, 5), umbilical cord blood (6), and the placenta (7).

Does the imprinting of the adaptive intestinal immune system begin before birth?

Accordingly, the development of the gut’s adaptive immune system may already begin in utero. This suggests that the critical period for establishing intestinal homeostasis may begin before birth (8).
Despite these findings, few studies have investigated the antigens present in the womb or the metabolites that influence…