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SGN-15 is a chimeric murine monoclonal antibody.
Ross et al. 2006 Lung Cancer 54: 69-77
It targets with BR96 mAb Lewis Y (Le y ) antigen conjugated to doxorubicin.
Ross et al. 2006 Lung Cancer 54: 69-77
SGN-15 was active against Le y -positive tumors in early phase clinical trials and was synergistic with docetaxel in preclinical experiments.
Ross et al. 2006 Lung Cancer 54: 69-77