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BR96 mAb, conjugated to doxorubicin and docetaxel (= ADC), was tested in phase II trials for advanced NSCLC (Ross et al. 2006 Lung Cancer 54: 69-77) and for metastatic breast cancer ()
Although initial results of BR96 mAb, conjugated to doxorubicin and docetaxel, were encouraging, the mAb was later discontinued, likely due to low efficacy (= ADC)
Rodrigues Mantuano et al. 2020
The antibody is directed against the [Lewi…