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There is a potential therapeutic potential of targeting glucocerebrosidase in the treatment of Morbus Parkinson / Parkinson's Disease (PD)-
The link between Gaucher disease and Morbus Parkinson / Parkinson's Disease (PD) was initially observed in clinical settings. It was noted that individuals with Gaucher disease and their carrier relatives showed a higher incidence of Morbus Parkinson / Parkinson's Disease (PD). Presently, mutations in the glucocerebrosidase (GBA1) gene are identified as the most prevalent genetic risk factor for both Parkinson’s disease and dementia with Lewy bodies. There is …