CD28

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CD28 binds to CD80, CD86 meaning fulminant T cell activation
Lines et al. 2014 Cancer Immunol Res 2(6): 510

CD28-CD86 interaction being the weakest
Walker & Sansom, 2011

[CD28] is expressed on T cell subsets and activated B cells as receptor for the co-stimulatory signal 2 (binding CD80 and CD86) to activate naive T cells
[Murphy 2012 Garland Science ISBN 978-0-8153-4243-4](brain://9A4OnaOh4Ei23Z9tb3AChw/Murphy2012…

References (Sources)

Janeway’s Immunobiology
Murphy 2012 Garland Science ISBN 978-0-8153-4243-4
The CD28 signaling pathway regulates glucose metabolism
Frauwirth et al. 2002 Immunity 16: 769-777
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell respons
Walker & Sansom, 2011
VISTA Is a Novel Broad-Spectrum Negative Checkpoint Regulator for Cancer Immunotherapy
Lines et al. 2014 Cancer Immunol Res 2(6): 510

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CD28

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