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Bacillus Haemolytic Enterotoxin (HBL) is the major virulence factor of human pathogen Bacillus cereus
Bacillus cereus produces and secrets the pore-forming Bacillus cereus hemolysin BL (HBL) as an exotoxin, that can lyse a wide range of mammalian cells. This interacts primarily with LPS-induced TNF-a factor (LITAF) (LPS-induced TNF-a factor), the HBL receptor on mammalian cells. Alternatively, Bacillus haemolytic enterotoxin (HBL) can interact with [Cell Death-Inducing p53 Target 1 (CDIP1)](b…