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Fusobacterium nucleatum is enriched in the gut of Rheumatoid Arthritis (RA) patients and aggravates arthritis by delivering the virulence factor FadA to the joints via outer membrane vesicles. Mechanistically, FadA triggers Synovial inflammation by activating the Rab5a-YB-1 axis in synovial macrophages
Hong et al. 2023 Cell Host & Microbe 31(5):
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