Fusobacterium nucleatum (Fn) is a commensal microorganism and an opportunistic pathogen contributing to local and systemic diseases (1-5). It is linked to inflammation and cancer (7).

Where is Fusobacterium nucleatum (Fn) typically found?

It is typically found in the human oral microbiota.
Fusobacterium nucleatum can spread from the oral cavity through the …

An antisense oligomer conjugate with unpredicted bactericidal activity against Fusobacterium nucleatum
Cosi et al. 2025 mBio 16: e00524-25
Expanding the genetic toolkit helps dissect a global stress response in the early-branching species Fusobacterium nucleatum
Ponath et al. 2022 Proc Natl Acad Sci USA 119: e2201460119
Fusobacterium nucleatum associates with stages of colorectal neoplasia development, colorectal cancer and disease outcome
Flanagan et al., 2014
Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis
Mima et al. 2016 Gut 65: 1973-1980
Fusobacterium nucleatum: an emerging gut pathogen?
Allen-Vercoe et al. 2011 Gut Microbes 2: 294-298
Fusobacterium nucleatum: ecology, pathogenesis and clinical implications
Jiang et al. 2026 Nat Rev Microbiol 24: 197-214
Review
Stratification of Fusobacterium nucleatum by local health status in the oral cavity defines its subspecies disease association
Krieger et al. 2024 Cell Host & Microbe 32(4): 479-488

10/17/2026

Fusobacterium nucleatum