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Interleukin-6 (IL-6) has been hypothesized to facilitate the growth and progression of some malignancies by increasing angiogenesis. Elevated IL-6 leads to the mobilization of myeloid-derived suppressor cells (MDSCs).
Granulocytic Myeloid-Derived Suppressor Cells (MDSCs) in Toll-like receptor 5 (TLR-5)-responsive tumors prompt gamma/delta cells to release galectin-1, which weakens [antitum…