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Myeloid suppressor cells (MDSCs) are a heterogeneous population of pathologically activated, mainly immature immunosuppressive myeloid cells.
Myeloid suppressor cells (MDSCs) arise in chronic inflammation, especially in late-stage cancer. Activation signals lead to different cell states in myeloid populations, leading to different suppressive modes.
Myeloid-Derived Suppressor Cells (MDSCs) induce immunosuppression. Treg depletion induces MDSC recruitment