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Specific gut microbiota can modulate the expression of Circular RNAs (circRNAs). For example, certain bacteria can suppress the expression of specific circRNAs, which subsequently affects MicroRNAs (miRNAs) levels and the expression of target genes involved in disease processes.
Beyond cancer, circRNAs are part of a broader group of host-derived molecules that interact with gut microbiota. These interactions are crucial for maintaining gut homeostasis and can be influenced by factors such as diet and environmental changes.
Exosomes, actively secreted by almost all cell types through an exocytosis pa…