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The human pathogen Helicobacter pylori produces a system to inject only a single protein, Chronic active gastritis A protein (CagA-Oncoprotein), into gastric cells, but this injection represents a major risk factor for gastric cancer development.
For that, it utilizes a type IV secretion system to interact with host cells and to modify their microenvironment in a favourable way.
see also:
Helicobacter pylori cagA(+) strains
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