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Gastric electrical rhythms (slow waves) are generated by Interstitial Cajal Cells (ICCs) and propagate around and down the stomach toward the antrum.
Interstitial Cajal Cells (ICCs) are recognized as the electrical pacemaker cells of the stomach.
Depletion of Cajal cells can interfere with slow cycles and induce gastric dysrhythmias, including tachygastria.
Chen et al. 1995 Dig Dis. 13(5): 275–90
O'Grady & Abell 2015 Gastroenterol Clin N Am. 44(1): 169–84
see also:
Gastroparesis & Pathophysiology…