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Fecal Microbiota Transplantation (FMT) from cancer patients who responded to a therapy wiht Immune Checkpoint Inhibitors (ICIs) (i.e., Anti-PD-1 antibodies / PD-1 inhibitors) into antibiotic-treated mice restored the efficacy of this therapy
In contrast, Fecal Microbiota Transplantation (FMT) from non-responder patients into antibiotic-treated mice failed to stimulate the response achieved with Anti-PD-1 antibodies / PD-1 inhibitors
see also:
Fecal Microbiota Transplantation (FMT) & Cancer Immunotherapy / Immuno-Oncology
Gut microbiota & Immune Checkpoint Inhibitors (ICIs)