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Vessel-lining endothelial cells execute distinct functions in response to stimuli from their microenvironment, such as an inflammatory stimulus or an angiogenesis-inducing cytokine
Endothelial cells as unique gatekeepers actively control organ function in an instructive manner by secreting paracrine-acting growth factors (angiokines), a novel signaling paradigm that has essentially been validated for most organs.
see also:
Vascular Wall / Blood Vessel
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