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Enterococcus gallinarum strain MRx0518 is a live biotherapeutic candidate derived from a human gut isolate that is being developed primarily for its immunostimulatory and antitumor properties. It is characterized by strong TLR-5‑driven activity via its flagellin, which is considered the key effector molecule for its immune effects (1).
It is administered orally as a live biotherapeutic (not a conventional probiotic food supplement) with a defined, pharmaceutical‑grade formulation
The strain’s flagellin potently activates Toll‑like receptor 5 (TLR5) on [innate immune cells](brain://bvQpgr3V4U6KUzq1…