Loading…
Please register to continue your trial period!
meRfi Microbiome provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Galectin-1 interacts with Myeloid-Derived Suppressor Cells (MDSCs) by by boosting their expansion
In several preclinical cancer models in immunogenic mice, galectin-1 promoted Chemokine (C-X-C motif) ligand 2 (CXCL2)-mediated accumulation of Polymorphonuclear Myeloid-Derived Suppressor Cells (PMN-MDSCs) in the premetastatic niche, thereby altering the local microenvironment and supporting metastasis
Mechanistically, galectin-1 maintained [NFKB activation](brain://GMpzV2KgAk6TkzDhQzvzoA/NfkbActivat…