Soft Tissue Sarcoma (STS)

Soft tissue sarcomas (STS) are a heterogeneous group of solid mesenchymal tumors, comprising more than 150 histological subtypes in the most recent classification. The number of distinct entities identified continues to increase over time. Despite their diversity, STS are rare, collectively accounting for less than 1% of all adult solid malignant cancers.

The extreme rarity and distinct natural course of individual subtypes present multiple challenges.

Subtypes (Examples)

Liposarcoma includes the following varieties:

• Atypical lipomatous tumor


• Dermatofibrosarcoma protuberans (includes pigmented varieties)


• Dermatofibrosarcoma protuberans, fibrosarcomatous


• Giant cell fibroblastoma


• Malignant solitary fibrous tumor


• Inflammatory myofibroblastic tumor
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