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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

LITAF (LPS-induced TNF-a factor)

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LITAF (LPS-induced TNF-a factor) is a transcription factor that plays a significant role in mediating inflammatory responses, particularly in the context of lipopolysaccharide (LPS) stimulation
Tang et al. 2006 Proc Natl Acad Sci USA 103(37): 13777-82

It regulates the expression of several pro-inflammatory cytokines, including:

Tang et al. 2006 Proc Natl Acad Sci USA 103(37): 13777-82

Studies have shown that LITAF-deficient mice express reduced levels of t…

LPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways
Tang et al. 2006 Proc Natl Acad Sci USA 103(37): 13777-82
Sequential CRISPR-Based Screens Identify LITAF and CDIP1 as the Bacillus cereus Hemolysin BL Toxin Host Receptors
Liu et al. 2020g Cell Host & Microbe 28: 402-410

7/1/2026