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The vaginal mucosal epithelium mainly consists of epithelial cells. However, both recruited and resident immune cells can significantly influence tissue-level immunity. Activating vaginal mucosal dendritic cells, which make up less than 1% of the total cell population, was enough to provide protection against vaginal viral infection. Applying aminoglycoside antibiotics directly to the skin boosts the body's defense against viral infections without relying on the microbiota.
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