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Sporadic colorectal cancer has traditionally been viewed in older individuals. However, as the global prevalence of the disease diagnosed in younger individuals (<50 years) is expected to increase within the next decade, greater recognition is now being given to early-onset colorectal cancer
Mutations that develop during an individual's lifetime can lead to a form of colorectal cancer (CRC) known as sporadic CRC. These mutations impact specific cells and their descendants. Notably, sporadic CRC represents about 95% of all CRC cases. CRC derived from mutations (caused by a mutation in the adenomatous polyposis coli gene (APC)) (Gao et al. …