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70 percent of patients with Crohn’s disease experience anastomotic recurrence within one year following ileo-caecal surgery. Recent clinical trials indicate that probiotics may be beneficial in managing intestinal inflammation associated with pouchitis and ulcerative colitis (1)
It is a a multicenter, prospective, randomized, double-blind, placebo-controlled parallel-group trial studying Lactobacillus johnsonii LA1 (10^10 CFU/day, freeze-dried powder in sachets, given daily for 12 weeks) or placebo (maltodextrin) in 70 randomized patients with Crohn’s disease (CD) after “curative” ileal, ileocolonic, or colonic resection (all macroscopic lesions removed) over 12 week…