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In general, this means reducing side effects and/or improving effectiveness. However, the strongest review-level evidence is for supportive-care outcomes such as diarrhea and oral mucositis rather than improving antitumor efficacy
A systematic review and meta-analysis, identified by the code CRD42022312083, examined the effects of probiotic supplementation for the prevention or treatment of chemotherapy and/or radiotherapy-related diarrhoea. This study included 18 randomized clinical trials (RCTs) conducted up to February 2022.
The analysis demonstrated that probiotics ha…