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Aromatase inhibitors are a foundational endocrine therapy for Breast cancer / Mammacarcinoma (HR+ Her2-), typically used in postmenopausal patients to reduce estrogen synthesis and tumor growth. Aromatase inhibitors block the aromatase enzyme, reducing peripheral estrogen production, which limits stimulation of HR+ breast cancer cells. Indicated primarily for postmenopausal women with HR+ (ER/PR+) breast cancer, including early-stage and metastatic settings.
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