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Arginyl-tRNA–protein transferase (ATE1) is an enzyme that plays a crucial role in the post-translational modification of proteins through a process called arginylation. This modification involves the addition of an arginine residue to the N-terminus of proteins, which can significantly alter their stability and function. ATE1 is a key component of the Arg/N-degron pathway, which targets proteins for degradation based on their N-terminal residues
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