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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Adverse Events / Safety & Ipilimumab

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In clinical trials, adverse events (AEs) related to treatment with ipilimumab were mostly grade 1/2 (as per Common Terminology Criteria for AEs, Version 4.02), and mostly reversible with appropriate management.
Lacouture et al., 2014

References (Sources)

ClinicalTrials.gov for Facilitating Rapid Understanding of Potential Harms of New Drugs: The Case of Checkpoint Inhibitors
Yang et al. 2018a
Immune related adverse events associated with anti-CTLA-4 antibodies: systematic review and meta-analysis
Bertrand et al., 2015
Ipilimumab in patients with cancer and the management of dermatologic adverse events
Lacouture et al., 2014
Review
Ipilimumab in the treatment of melanoma
Trinh & Hwu 2012
Randomized, Open-Label Phase II Study Evaluating the Efﬁcacy & Safety of Talimogene Laherparepvec in Combination with Ipilimumab Vs Ipilimumab Alone in Pts with Advanced, Unresectable Melanoma
Chesney et al. 2018
Safety profiles of anti-CTLA‑4 and anti‑PD‑1 antibodies alone and in combination
Boutros et al. 2016
Update on the role of ipilimumab in melanoma and first data on new combination therapies
Maio et al. 2013
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7/1/2026

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