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This means reducing side effects and/or improving effectiveness.
see also:
Adverse Events / Safety & Anti-CTLA-4 / CTLA-4
Adverse Events / Safety & Anti-PD-1 antibodies / PD-1 inhibitors
Adverse Events / Safety & Anti-PD-L1 antibodies / PD-L1 inhibitors
[Adverse Events / Safety & Immune Checkpoint Inhibitors (ICIs)]