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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

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Escitalopram + Lactiplantibacillus plantarum & Major depressive disorder / Major Depression / Depressive episode (MDD)

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Clinical data

NCT02469545
Augmentation of Escitalopram treatment with probiotic bacteria Lactobacillus Plantarum 299v improved cognitive performance and decreased KYN concentration in major depressive disorder patients. Decreased KYN concentration could contribute to the improvement of cognitive functions in the LP299v group compared to the placebo group. Results of this study are the first evidence of improvement…

References (Sources)

Probiotic lactobacillus plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: A double-blind, randomized, placebo controlled study
Rudzki et al. 2019 Psychoneuroendocrinology 100: 213-222
The effects of Lactobacillus plantarum PS128 in patients with major depressive disorder: an eight-week double-blind, placebo-controlled study
Lin et al. 2024 Asian J Psychiatr 101: 104210

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