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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Enterochromaffin-like cell (ECL)

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Enterochromaffin-like cell (ECL) are located in the stomach without contact with the lumen. They produce histamine and serve to stimulate gastric acid secretion
Furness et al. 2013a Nature Reviews Gastroenterology & Hepatology 10: 729-740

Named for Similarity to Enterochromaffin Cells (EC). The identifying hormone (historically) is

Histamine

Examples of colocalization of hormones and/or their gene transcripts (most of recent data is from mouse):

Pancreastatin / Chromogranin-A

Fothergill & Furness 2018 Histoche…

References (Sources)

Diversity of enteroendocrine cells investigated at cellular and subcellular levels: the need for a new classification scheme.
Fothergill & Furness 2018 Histochem Cell Biol 150(6): 693-702
Review
The biology and physiology of the ECL cell
Hakanson et al. 1994 Yale J. Biol. Med. 67: 123-134
Review
The gut as a sensory organ
Furness et al. 2013a Nature Reviews Gastroenterology & Hepatology 10: 729-740
Review

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Enterochromaffin-like cell (ECL)

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