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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Adiposity / Obesity & Glucagon Like Peptide 1 (GLP-1)

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After eating, the body's Glucagon Like Peptide 1 (GLP-1) response usually stays the same no matter how much body fat a person has. However, subtle deficits in GLP-1 function might play a role in metabolic problems linked to obesity.
Lopes et al. 2023 Arch Endocrinol Metab 67(4): e000611
Eriksen et al. 2024 The Journal of Clinical Endocrinology & Metabolism 109(9): e1697-e1707

GLP-1 is a hormone made mainly in the gut and brainstem. It helps the body release insulin when blood sugar levels…

References (Sources)

Ghrelin and glucagon-like peptide-1 according to body adiposity and glucose homeostasis
Lopes et al. 2023 Arch Endocrinol Metab 67(4): e000611
GLP-1 physiology informs the pharmacotherapy of obesity
Drucker 2022 Mol Metab 57: 101351
Review
Glucagon-like peptide 1 in the pathophysiology and pharmacotherapy of clinical obesity
Anandhakrishnan & Korbonits 2016 World J Diabetes 7(20): 572-598
Gut hormones and appetite control: a focus on PYY and GLP-1 as therapeutic targets in obesity
De Silva & Bloom, 2012 Gut Liver 6(1): 10-20
Review
The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study
Eriksen et al. 2024 The Journal of Clinical Endocrinology & Metabolism 109(9): e1697-e1707

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Adiposity / Obesity & Glucagon Like Peptide 1 (GLP-1)

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