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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

RAR-related orphan receptor gamma/t (ROR-gamma/t) Isoform 2 (NR1F3) & T helper 17 cell (Th17)

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IL17 / RAR-related orphan receptor gamma/t (ROR-gamma/t) Isoform 2 (NR1F3) Deﬁcient CD4 T Cells Induce type 2 diabetes and Adiposity / Obesity
Garidou et al. 2015

In the intestine, CD4 T cells contribute to immunity. They differentiate into subgroups representing inflam…

CD4(+) T-cell subsets in intestinal inﬂammation
Shale et al. 2013 Immunol. Rev. 252: 164-182
Review
Controlling the frontier: regulatory T-cells and intestinal homeostasis
Bollrath & Powrie 2013 Semin. Immunol. 25: 352-357
Review
Development and Survival of Th17 Cells within the Intestines: The Influence of Microbiome- and Diet-Derived Signals
Chewning & Weaver 2014 J Immunol 193(10): 4769-4777
Review
ROR gamma t and ROR alpha signature genes in human Th17 cells
Castro et al. 2017a
RORgamma/t protein modifications and IL17-mediated inflammation
Kumar et al. 2021b Trends in Immunology 42: 1037
Review
Th17 and regulatory T cells in mediating and restraining inﬂammation
Littman & Rudensky 2010 Cell 140: 845-858
Review
The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORgammat and Controls Metabolic Disease
Garidou et al. 2015

7/1/2026