Start
Features
Free trial / FAQ

Researchers
Physicians
Pharmacists
Ecotrophologists
Product Managers
in Health Industries

Loading…

Medical Research Finder

Legal Notice
Privacy
Terms of Use

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

meRfi® AI Chat

ATP & Inflammation / Inflammatory diseases

Welcome to meRfi Microbiome!

Please register to continue your trial period!

meRfi Microbiome provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.

Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.

Start your free trial and transform your understanding of the gut microbiota today!

(Login)

Navigation

ATP exhibits both pro-inflammatory and anti-inflammatory properties, with its activity mediated through P2 receptors, specifically P2X and P2Y.

Bildschirmfoto 2024-07-07 um 11.46.33

Pro-inflammatory-related properties of ATP

In the lamina propria, ATP promotes the differentiation of naive CD4+ T Cells into T helper 17 cell (Th17). This process is induced by the [pro-inflammatory cytokines](brain://EvjM4rCIkUKzDb5xLJSSWA/ProinflammatoryCytokine…

References (Sources)

ATP drives lamina propria Th17 cell differentiation
Atarashi et al. 2008 Nature 455: 808-812
Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine
Kusu et al. 2013 J. Immunol. 190: 774–783
The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets
Allard et al., 2017
Review
Understanding the Holobiont: How microbial metabolites affect human health and shape the immune system
Postler & Ghosh 2017
Review

AI Chat

7/1/2026

Chat with our artificial intelligence:

Start chat!