Food antigens

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What is the most common immune response after exposure to food antigens?

Exposure to food antigens that can trigger a type 2 immunity is common.
Delaroque et al. 2025 Gut Microbes 17(1): 2590830

How does the immune system respond to harmless food and gut microbial antigens?

The immune system encounters many harmless antigens from food and intestinal commensal microbes. It normally responds to these antigens with appropriate, non-inflammatory immune reactions.
Kedmi & Littman 2024 Immunity 57(10): 2269-2279

References (Sources)

Antigen-presenting cells as specialized drivers of intestinal T cell functions
Kedmi & Littman 2024 Immunity 57(10): 2269-2279
Context-dependent roles of the gut microbiome in food allergy tolerance versus sensitization
Delaroque et al. 2025 Gut Microbes 17(1): 2590830
Review
Food-Specific Serum IgG4 and IgE Titers to Common Food Antigens in Irritable Bowel Syndrome
Zar et al. 2005 Am J Gastroenterol 100: 1550–1557
How Changes in the Nutritional Landscape Shape Gut Immunometabolism
Tan et al. 2021b Nutrients 13: 823
Review
Local immune response to food antigens drives meal-induced abdominal pain
Aguilera-Lizarraga et al. 2021

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