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Almost every aspect of Large Granular Lymphocytes / NK-cells (CD3 -CD56 +) immunity is regulated by Interleukin-15 (IL-15)
Interleukin-15 (IL-15) is a pleiotropic cytokine that promotes the survival, proliferation, and cytotoxicity of both Large Granular Lymphocytes / NK-cells (CD3 -CD56 +) and CD8+ T-Cell / Cytotoxic T Cell (CTL). As these cells take the lead in tumor destr…