Pediatric Crohn's disease (CD)

• Epidemiological studies indicate a notable rise in Crohn's disease (CD) cases in Western countries, particularly in children (1, 2, 3, 4)


• The disease's pathogenesis is influenced by host genetics and environmental factors (1, 2, 3, 4)


• Diet and the intestinal microbiome are key etiological components (1, 2, 3, 4)

References

(1) Renz et al. 2011 Nat Immunol 12: 273-277
(2) Kaplan & Ng 2017 Gastroenterology 152: 313-321
(3) Kuenzig et al. 2022 Gastroenterology 162: 1147-1159
(4 Liu et al. 2023m Nat Genet 55: 796-806

see also:
Exclusive Enteral Nutrition (EEN) & Crohn’s Disease (CD)

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