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Richter's syndrome, also known as Richter's transformation, is a rare and aggressive complication that can occur in patients with chronic lymphocytic leukemia (CLL). It is characterized by the transformation of the indolent CLL into a high-grade and rapidly progressing lymphoma, most commonly Large B-cell lymphoma (LBCL) / Diffuse Large B-Cell Lymphoma (DLBCL) .
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