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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Microbial Ecosystem Therapeutics 2 (MET-2) & Major depressive disorder / Major Depression / Depressive episode (MDD)

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NCT04052451
is groundbreaking as it offers the first evidence supporting the role of Microbial Ecosystem Therapeutics 2 (MET-2) in the treatment of Major depressive disorder / Major Depression / Depressive episode (MDD). Nevertheless, to achieve more definitive results, it is essential to conduct a double-blind, randomized controlled trial with a larger sample size (1).

(1) Meyyappan et al. 2022 Interact J Med Res 11(1): e32234

see also:
[Major depressive disorder / Major Depression / Depressive episo…

Microbial Ecosystem Therapeutic-2 Intervention in People With Major Depressive Disorder and Generalized Anxiety Disorder: Phase 1, Open-Label Study
Meyyappan et al. 2022 Interact J Med Res 11(1): e32234
The Safety and Efficacy of Microbial Ecosystem Therapeutic-2 in People With Major Depression: Protocol for a Phase 2, Double-Blind, Placebo-Controlled Study
Meyyappan et al. 2021 JMIR Res Protoc 10(9): e31439

7/1/2026