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Supplementing probiotics to modify the microbial ecology in the human gut may serve as an alternative strategy to alleviate or prevent depression (1).
It is a randomized, placebo-controlled clinical trial studying Heyndrickxia coagulans MTCC 5856 tablets (daily 600 mg) that contained 2 billion spores (333.33 mg) or placebo for 90 days in 40 patients (analyzed) with Major depressive disorder / Major Depression / Depressive episode (MDD) plus Irritable Bowel Syndrome (IBS) (1)
A mean 90-day change in depression and IBS symptoms as as…